Kinetics Investigation on Mushroom Tyrosinase Inhibition of Proso Millet
نویسندگان
چکیده
منابع مشابه
The inhibition effects of melon on mushroom tyrosinase activity
The inhibition effects seed and peel of melon on diphenolase activity of mashroom tyrosinase were investigated. The IC50 values and Ki values of seed and peel of melon were evaluated. increased the Km value and decreased the Vm value so it show mixed type inhibition on mushroom tyrosinase when L-DOPA was used as a substrate.
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Currently, aloesin is used in the cosmetic industry as a whitening agent because it inhibits tyrosinase activity. Aloesin is a C-glycosylated chromone compound isolated from aloe, and it is difficult to synthesize because of C-glycosyl moiety in the molecule. The purpose of this study is to search for a new chromone compound which is easy to synthesize and which posesses stronger tyrosinase inh...
متن کاملPhytochemical and Antiproliferative Activity of Proso Millet
The phytochemical content, antioxidant activity and antiproliferative properties of three diverse varieties of proso millet are reported. The free phenolic content ranged from 27.48 (Gumi 20) to 151.14 (Mi2504-6) mg gallic acid equiv/100 g DW. The bound phenolic content ranged from 55.95 (Gumi20) to 305.81 (Mi2504-6) mg gallic acid equiv/100 g DW. The percentage contribution of bound phenolic t...
متن کاملKinetics of Mushroom Tyrosinase and Melanogenesis Inhibition by N-Acetyl-pentapeptides
We investigated the kinetics of 4N-acetyl-pentapeptides, Ac-P1, Ac-P2, Ac-P3, and Ac-P4, regarding inhibition of mushroom tyrosinase activity. The peptides sequences of Ac-P1, Ac-P2, Ac-P3, and Ac-P4 were Ac-RSRFK, Ac-KSRFR, Ac-KSSFR, and Ac-RSRFS, respectively. The 4N-acetyl-pentapeptides were able to reduce the oxidation of l-DOPA by tyrosinase in a dose-dependent manner. Of the 4N-acetyl-pen...
متن کاملkinetic of mushroom tyrosinase inhibition by benzaldehyde derivatives
polyphenol oxidase (ppo), also known as tyrosinase (ec 1.14.18.1), is a copper-containing enzyme widely distributed in microorganisms, animals, and plants. this enzyme is responsible not only for browning in plants but also for melanization in animals. thus, tyrosinase inhibitors have a huge impact on industry and the economy. in the current study, we first purified the enzyme, then evaluated i...
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ژورنال
عنوان ژورنال: Journal of Chemistry
سال: 2018
ISSN: 2090-9063,2090-9071
DOI: 10.1155/2018/2387926